You can analyze anything ad nauseam. But at the same time, you can't grasp anything from nature in its totality because nature itself is infinitely complex. So you need to know what is possible to grasp from subjective experience. Things that "noticably" stand out to to us through our senses. And of all those things, what is most important "standing out" part about the thing you want to learn about? The "difference which makes a difference".